SLF
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SLF is a new algorithm designed to refill WM lesions on MRI T1-w images. For each slice composing the three-dimensional brain image, lesion voxel intensities are replaced by random intensities of a normal distribution generated from the mean white matter intensity of the current slice. The algorithm recomputes the mean white matter signal intensity at each two-dimensional slice with the aim of reproducing more precisely the signal variability between MRI slices, especially in low resolution images.
Currently, SLF is currently available to download both as a ready-to-use Matlab function and as a SPM library. The useful resources section contains all available software source-codes as zip files. Please check the Requirements tab before installing it.
Besides, documentation tab contains links to other repositories containing other existing lesion-filling algorithms.